HIV/AIDS Therapy

Leptin levels linked to antiretroviral-induced immune recovery

Published in AIDS Weekly, January 6th, 2003

by Michael Greer, senior medical writer - Leptin levels may be linked to immune recovery after antiretroviral therapy in pediatric HIV patients, researchers in Italy report.

"Because leptin, the adipocyte-derived hormone, affects thymocyte survival, proliferation of naive T lymphocytes and the production of proinflammatory cytokines, we aimed to investigate the role of this molecule in immunoreconstitution during highly active antiretroviral therapy (HAART)," explained G. Matarese and colleagues at the National Research Center, the Institute of Endocrinology and Experimental Oncology, the University of Napoli, and the V. Monaldi Company Hospital in Napoli and the...

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Source: AIDS Weekly (2003-01-06)

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