HIV/AIDS Therapy
Viral envelope glycoproteins show antibacterial activity
Published in AIDS Weekly, March 17th, 2003
"Recent reports have highlighted the anti-HIV-1 activities of defensins, whose structure and charge resemble portions of the HIV-1 transmembrane envelope glycoprotein gp41," explained researchers at the University of California.
A. M. Cole and colleagues investigated "the obverse, whether peptides derived from HIV-1 envelope glycoproteins can exert antimicrobial activity."
"Fifteen-residue peptides spanning the entire sequence of HIV-1(MN) gp120 and gp41 were subjected to radial diffusion assays against laboratory strains of Escherichia coli and Listeria...
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Source: AIDS Weekly (2003-03-17)
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