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Cell Biology

Researchers identify protein that helps HIV penetrate cells

Published in AIDS Weekly, March 24th, 2003

Scientists at the University of Texas Medical Branch at Galveston (UTMB) have identified a crucial link in the process that HIV uses to get inside one kind of human white blood cells.

A discovery reported in the March 16, 2003, Journal of Virology, ultimately could lead to new therapies that researchers hope might block the entry of HIV into some white blood cells, thus slowing the reproduction of the virus.

Led by Professor William A. O'Brien, UTMB researchers Jana J. von Lindern, Daniel Rojo, Cheng Deng, Georges Herbein, Monique Ferguson and Todd C. Pappas implicated a protein known as CD63 in the intricate dance of biochemical reactions...

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