Published in AIDS Weekly, April 28th, 2003
According to recent research from the United States, "the V3 loop and the bridging sheet domain of human immunodeficiency virus type 1 (HIV-1) subtype B envelope glycoprotein gp120 have been implicated in CCR5 coreceptor utilization."
P. Suphaphiphat and coauthors at Harvard University conducted a study in which "mutant envelope glycoproteins of a subtype C isolate containing substitutions in the V3 or C4 region were generated to determine which are required for efficient CCR5-dependent cell fusion and viral entry."
The results showed...
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