Published in AIDS Weekly, April 28th, 2003
TCS "is a type I ribosome-inactivating (RI) protein possessing multiple biological and pharmacological activities," researchers in China explained. "Its major action is inhibition of human immunodeficiency virus (HIV) replication but the mechanism is still elusive."
"Previous studies found that TCS mutants with reduced RI activity simultaneously lost some anti-HIV activity," noted J.H. Wang and coauthors at the Chinese Academy of Sciences.
However, "an exception was demonstrated by two TCS mutants retaining almost all RI activity but were...
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