HIV/AIDS Vaccine

T-cell responses in persistently seronegative women characterized

Published in AIDS Weekly, April 28th, 2003

by Michael Greer, senior medical writer - Vaccine researchers in the United States and Thailand have elucidated the HIV-specific T-cell profile in "highly exposed but persistently seronegative" women (HW).

Nattawan Promadej and colleagues at the Centers for Disease Control and Prevention and Emory University's Vaccine Research Center in Atlanta, Johns Hopkins University in Baltimore, and the Research Institute of Health Science in Chiang Mai, Thailand examined a cohort of HWs and their HIV-infected partners.

Virus-specific T-cell activity was less extensive in HWs compared to their seropositive partners, but was "remarkably" persistent in the absence...

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Source: AIDS Weekly (2003-04-28)

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