Published in AIDS Weekly, May 19th, 2003
"Retroviral recombinants result from template switching between copackaged viral genomes," explained A. Onafuwa and colleagues.
When these University of Michigan researchers measured "marker reassortment between coexpressed vectors ... during single replication cycles," they found HIV-1 recombination occurred six to seven times more frequently than murine leukemia virus (MLV) recombination.
The researchers reported that they also assayed "template switching ... using...
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