HIV/AIDS Therapy
Caffeine inhibits retroviral DNA integration
Published in AIDS Weekly, June 9th, 2003
"Caffeine is an efficient inhibitor of cellular DNA repair, likely through its effects on ATM (ataxia telangiectasia mutated) and ATR (ATM and Rad3-related) kinases," researchers in the United States noted.
In a recent study, R. Daniel and coauthors at the Fox Chase Cancer Center in Philadelphia found that "caffeine treatment causes a dose-dependent reduction in the total amount of HIV-1 and avian sarcoma virus retroviral vector DNA that is joined to host DNA in the population of infected cells and also in the number of transduced cells."
"These changes were observed...
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Source: AIDS Weekly (2003-06-09)
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