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Patents

New manufacturing patent issued for AIDS vaccine, cystic fibrosis and arthritis programs

Published in AIDS Weekly, June 16th, 2003

Targeted Genetics Corporation (NASDAQ:TGEN) announced the issuance of an additional patent related to its adeno-associated virus (AAV) vector manufacturing process. U.S. Patent No. 6,566,118 is titled, "Methods for generating high titer helper-free preparation of released recombinant AAV vectors."

The patent describes an AAV manufacturing process in which the growth conditions used to culture the production cells lead to the release of vector particles into the cell culture medium without the need for breaking open the host cell membrane. This approach leads to improved production quality and allows for a more cost-effective approach to large-scale manufacturing of AAV...

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