HIV/AIDS Vaccine

Cytotoxic T lymphocyte-based strategies ineffective over long term

Published in AIDS Weekly, July 7th, 2003

by Michael Greer, senior medical writer - HIV vaccine strategies based on inducing antiviral cytotoxic T lymphocyte (CTL) responses may not be effective over the long term, researchers in the United States warn.

Virus-specific CTL "are critical for control of human immunodeficiency virus type 1 replication," explained Dan H. Barouch and colleagues at Harvard Medical School in Boston and Northwestern University Medical School in Chicago. "However, viral escape from CTL recognition can undermine this immune control."

Barouch and coauthors found a very high rate of viral escape during long-term follow-up of immunized macaques, according to the report of...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of AIDS Weekly

Source: AIDS Weekly (2003-07-07)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry