Published in AIDS Weekly, August 4th, 2003
Highly attenuated MVA "serves as a candidate vaccine to immunize against infectious diseases and cancer," including HIV infection, explained Simone Hornemann and colleagues at Ludwig Maximilians University in Munich and the Technical University of Munich.
A mutant form of MVA lacking expression of the IFN resistance gene E3L was unable to replicate in chicken embryo fibroblasts (CEF) used in experimental tissue cultures, Hornemann and coauthors...
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