HIV/AIDS Genomics and Genetics

Standardized editing guidelines needed for HIV genotyping

Published in AIDS Weekly, September 8th, 2003

Standardized editing guidelines are needed for scientists performing HIV genotyping.

"Sequencing-based human immunodeficiency virus type 1 (HIV-1) genotyping assays require subjective interpretation (editing) of sequence data from multiple primers to form consensus sequences and identify antiretroviral drug resistance mutations," researchers in the United States explained.

In their study, D.D. Huang and coauthors at Rush Medical College in Chicago "assessed interlaboratory variations in editing and their impact on the recognition of resistance mutations."

"Six samples were analyzed in a central laboratory by using a...

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Source: AIDS Weekly (2003-09-08)

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