Immunology

Biologist finds HIV gene makes a human gene turn bad

Published in AIDS Weekly, September 8th, 2003

A human gene named ATR normally protects people by preventing the replication of cells damaged by radiation or toxic chemicals. Now, Utah and New York researchers have discovered how a gene in the AIDS virus hijacks the human gene and turns it into a weapon that prevents reproduction of immune system white blood cells, leaving AIDS patients vulnerable to deadly infections and cancer.

The new study "puts us a big step closer to understanding how HIV dismantles the immune system," said molecular biologist Vicente Planelles, an associate professor of pathology at the University of Utah School of Medicine.

It also raises the prospect for new kinds of...

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Source: AIDS Weekly (2003-09-08)

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