HIV/AIDS Therapy
RNA-based gene therapy techniques show promise for HIV control
Published in AIDS Weekly, September 15th, 2003
"Gene therapy strategies for HIV infection require gene transduction of hematopoietic stem cells with effective therapeutic constructs," scientists in the United States noted.
In a recent study, R. Akkina and colleagues at Colorado State University evaluated the efficacy of "anti-HIV ribozymes, RNA decoys and the newly described siRNAs."
"The therapeutic constructs consisted of an anti-CCR5 ribozyme to downregulate the HIV-1 cell surface co-receptor and ribozynmes targeted to viral mRNAs coding for the Tat, Rev and Env proteins," they explained. "The RAA decoy...
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Source: AIDS Weekly (2003-09-15)
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