Immunology

Scientists: Cloak of human proteins gets HIV into cells

Published in AIDS Weekly, September 15th, 2003

Three Johns Hopkins researchers propose, for the first time, that HIV and other retroviruses can use a Trojan horse style of infection, taking advantage of a cloak of human proteins to sneak into cells.

The hypothesis explains 20 years of perplexing observations and suggests new ways to reduce HIV transmission and treat HIV infection, but it also implies that existing approaches to developing vaccines against HIV won't work. A description of the hypothesis and its supporting evidence appeared online the week of August 29 in the Proceedings of the National Academy of Sciences USA.

"Most researchers have focused on viral proteins when trying to...

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Source: AIDS Weekly (2003-09-15)

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