HIV/AIDS
Compared with Italians, CXCR4 expression heightened in Indian HIV patients
Published in AIDS Weekly, September 22nd, 2003
In a recent study, scientists in Italy "extended the investigation of the virus-host interaction in developing countries by analyzing Indian HIV-infected and uninfected individuals from Maharashtra-Mumbai."
"Results showed that CXCR4 messenger RNA and surface expression, as well as IL-4 mRNA and T allele frequency at the -589 site in the IL-4 gene (high IL-4 production) were significantly increased in Indian compared with Italian individuals," reported M. Biasin and coauthors at the University of Milan.
"Because IL-4 stimulates CXCR4...
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Source: AIDS Weekly (2003-09-22)
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