HIV/AIDS Pathogenesis
MHC-I alleles linked to slow HIV progression bind dominant CTL epitopes during acute infection
Published in AIDS Weekly, September 22nd, 2003
"Certain major histocompatibility complex class I (MHC-I) alleles are associated with delayed disease progression in individuals infected with human immunodeficiency virus (HIV) and in macaques infected with simian immunodeficiency virus (SIV)," scientists in the United States explained. "However, little is known about the influence of these MHC alleles on acute-phase cellular immune responses."
D.H. O'Connor and colleagues at the Wisconsin Regional Primate Research Center examined "51 animals infected with SIVmac239" in their study.
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Source: AIDS Weekly (2003-09-22)
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