HIV/AIDS Opportunistic Infection
Novel Pneumocystis gene aids cell wall assembly
Published in AIDS Weekly, September 22nd, 2003
"Pneumocystis pneumonia remains the most common AIDS-defining opportunistic infection in people with HIV," researchers in the United States explained. "The process by which Pneumocystis carinii constructs its cell wall is not well known, although recent studies reveal that molecules such as beta-1-3-glucan synthetase (GSC1) and environmental pH-responsive genes such as PHR1 are important for cell-wall integrity."
"In closely related fungi, a specific mitogen-activated protein kinase (MAPK) cascade regulates cell-wall...
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Source: AIDS Weekly (2003-09-22)
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