HIV/AIDS Proteomics
HIV env gene plays key role in viral fitness
Published in AIDS Weekly, September 22nd, 2003
"A human host offers a variety of microenvironments to the infecting human immunodeficiency virus type I (HIV-1), resulting in various selective pressures, most of them directed against the envelope (env) gene," scientists in the United States explained. "Therefore, it seems evident that the replicative capacity of the virus is largely related to viral entry."
In their study, H.R. Rangel and colleagues at the Cleveland Clinic Foundation "used growth competition experiments and TaqMan real-time PCR detection to measure the fitness of subtype B HIV-1 primary...
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Source: AIDS Weekly (2003-09-22)
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