Pediatric HIV/AIDS
Resistance to CD4 cell loss may cause increased viral load in HIV-infected neonates
Published in AIDS Weekly, September 22nd, 2003
"Children with human immunodeficiency virus infection often have higher viral loads and progress to AIDS more rapidly than adults," scientists in Louisiana explained.
"Since the intestinal tract is a major site of early viral replication and CD4+ T-cell depletion in adults," R.S. Veazey and colleagues at Tulane University "examined the effects of simian immunodeficiency virus (SIV) on both peripheral and intestinal lymphocytes from 13 neonatal macaques infected with SlVmac239."
"Normal neonates had more CD4+ T cells and fewer CD8+ T...
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Source: AIDS Weekly (2003-09-22)
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