HIV/AIDS Therapy
High-performance LC assay improves measurement of plasma tenofovir levels
Published in AIDS Weekly, October 6th, 2003
According to published research from France, a "high-performance liquid chromatography assay was developed for the determination of tenofovir, a nucleotide analogue, in plasma."
"A solid-liquid extraction procedure was coupled with a reversed-phase HPLC system. The system requires a mobile phase containing Na2 HPO4 buffer, tetrabutylammonium hydrogen sulfate and acetonitrile for different elution through a C-18 column with UV detection," explained S. Sentenac and coauthors working at Pitie-Salpetriere Hospital in...
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Source: AIDS Weekly (2003-10-06)
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