HIV/AIDS Theapy
CCR5-disrupting molecules can prevent HIV infection
Published in AIDS Weekly, October 27th, 2003
"CCR5 is the major coreceptor for the HIV-1 strains responsible for primary infection," scientists in Madrid explained. "Individuals homozygous for a 32-bp deletion in the CCR5 coding region are resistant to HIV-1 infection. Strategies to delete CCR5 functionally could thus be of substantial benefit in preventing HIV-1 infection or delaying disease."
With this in mind, J.L. Abad and colleagues at the Centro Nacional de Biotecnologia in Madrid "evaluated new molecules for their ability to inhibit cell membrane CCR5 expression and to prevent HIV-1 infection."
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Source: AIDS Weekly (2003-10-27)
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