Oral Warts

IND application filed to test oral interferon alpha

Published in AIDS Weekly, November 10th, 2003

Amarillo Biosciences, Inc., (AMAR, ABI) announced filing of an investigational new drug (IND) application for a pivotal phase III trial to test low-dose interferon alpha lozenges administered orally to human immunodeficiency virus (HIV)-positive subjects with oral warts.

Viral lesions of the mouth in patients infected with HIV are common and may be indicative of disease progression. One of the causes of oral lesions is a group of DNA viruses, human papilloma viruses, which induce hyperplastic lesions in the oral soft tissue such as papillomas, warts, condylomata, and focal epithelial hyperplasia.

Oral warts cause a significant reduction in quality of...

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Source: AIDS Weekly (2003-11-10)

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