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HIV/AIDS

Reticulated platelet assay helps identify HIV-related ITP

Published in AIDS Weekly, November 10th, 2003

The RP assay can be used to distinguish normal and HIV-related immune thrombocytopenic purpura (ITP).

Diagnosis of ITP is currently "based on low platelet count and exclusion of clinical conditions rather than a specific diagnostic test," hematologists in Canada noted.

M.I.C. Gyongyossy-Issa and colleagues at the University of British Columbia "used the reticulated platelet (RP) assay to study ITP and thrombocytopenia associated with HIV infection (HIV-ITP)."

"Data from 96 ITP and 23 HIV-ITP patients showed low platelet counts (PC) with both high or low %RP suggesting that individuals have different degrees of thrombopoiesis,"...

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