Published in AIDS Weekly, November 17th, 2003
According to published research from the United States, "Predictive pharmacophore models were developed for a large series of piperidine- and piperazine-based CCR5 antagonists as anti-HIV-1 agents reported by Schering-Plough Research Institute in recent years."
"The pharmacophore models were generated using a training set consisting of 25 carefully selected antagonists based on well documented criteria," explained A.K. Debnath and coauthors working at the New York Blood Center.
"The activity spread, expressed in K-i, of training...
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