AIDS Weekly
Susan Hasty, Publisher
Table of Contents . . . December 8th, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in AIDS Weekly | Other Publications
Drug Development - Benzothiazolesulfonamides with potent activity against HIV protease synthesized
HIV/AIDS Therapy - AZT has cytotoxic effects on placenta in pregnant women
Drug Development - Ritonavir derivatives have potent anti-HIV activity, despite poor pharmacokinetics
HIV/AIDS Drug Resistance - Simplified ViroSeq HIV genotype test retains accuracy
HIV/AIDS Therapy - Fluorescence-based assay aids screening of potential HIV RT RNase H inhibitors
HIV/AIDS Therapy - Ritonavir and indinavir inhibit calpain activity
AIDS Epidemiology - China's AIDS epidemic is reaching "frightening" levels, renowned expert says
AIDS Epidemiology - Fewer AIDS babies born in U.S. but worldwide transmissions remain epidemic
AIDS Epidemiology - Study: About 4.5 million Indians have HIV
AIDS Prevention - AIDS vaccine trials begin in South Africa, Switzerland
AIDS Prevention - Experimental AIDS vaccine didn't stop HIV
AIDS Testing - VScan maker receives IRB approval for live testing
Antifungal Susceptibility - Clinical isolate fungi are mostly Candida; only amphotericin B acts on all
Blood-borne Disease - High theoretical risk of HIV, HCV transmission for forensic pathologists
Cachexia - Positive preliminary results reported on AVR118
Cancer Therapy - The zinc-chelating agent disulfiram may have anticancer applications
Collaborations - MWG Biotech announces agreement to automate HIV and HCV viral load assays
Correctional Healthcare - New York Assembly pushes for state oversight of prison healthcare
Dementia - Brain damage found in HIV patients on antiretroviral therapy
Diagnostics - Company receives exclusive rights to medical testing devices, supplies 10-minute HIV test
Drug Development - Improved stavudine derivatives developed
Feline Leukemia Risk - Host range of feline leukemia virus A could include human, as seen in vitro
Finance - AIDS vaccine developer reports increased cash due to financing
Finance - ESTRASORB maker announces increased third quarter revenue
Glomerulonephritis - CYC202 has beneficial effects in kidney disease models
HIV Prevention - Elements of green tea prevent HIV from binding to human T cells
HIV Tests - Company to donate HIV-1 lab tests to AIDS clinic in Africa
HIV/AIDS Cancer - Hypermethalation of MGMT, DAP-K underlie immunodeficiency-related lymphomas
HIV/AIDS Diagnosis - Newly approved rapid HIV-1 test is really rapid
HIV/AIDS Dyslipidemia - Nelfinavir downregulates LDL receptors involved in lipoprotein catabolism
HIV/AIDS Epidemiology - Novel recombinant subtype C HIV-1 strain found in Thailand
HIV/AIDS Gene Therapy - Small interfering RNAs can silence env in HIV-infected cells
HIV/AIDS Neurotoxicity - Oligodendrocyte Nef expression may underlie HIV-induced vacuolar myelopathy
HIV/AIDS Pathogenesis - Anti-Hsp70 antibody levels rise after HIV infection
HIV/AIDS Pathogenesis - Cyclophilin A needed for functional expression of HIV Vpr
HIV/AIDS Pathogenesis - Intrinsic and extrinsic apoptosis pathways both involved in SIV-induced T-cell loss
HIV/AIDS Proteomics - Solution structure of mature HIV protease monomer characterized
HIV/AIDS RNA Research - Human Nup98 aids HIV Rev-mediated RNA export
HIV/AIDS Therapy - Careful cervical monitoring needed for women failing HIV treatment
HIV/AIDS Therapy - Early SHIV control in monkeys causes long-lasting asymptomatic outcomes
HIV/AIDS Therapy - Efavirenz and nevirapine have comparable value as PI replacements
HIV/AIDS Therapy - Hyperlactatemia common during antiretroviral therapy
HIV/AIDS Therapy - Modified WHO therapy effective against chronic diarrhea in HIV patients
HIV/AIDS Therapy - Polymyositis can masquerade as antiretroviral-induced mitochondrial damage
HIV/AIDS Vaccine - Microarray profiling of antibody responses against SHIV developed
Immune Evasion - Human cytomegalovirus pp65 protein acts as an inhibitor of interferon response
Immunology - HLA markers linked to rapid AIDS progression may also raise CMV retinitis risk
Immunotherapy - HIV TAT-SpA fusion protein could be useful for cellular antibody delivery
Legal Issues - Nutra Pharma settles litigation, obtains license to intellectual property
Opportunistic Infection - Viable M. avium needed for enhanced HIV replication in monocytoid cells
Patents - European patent approved for HIV application
Pediatric HIV/AIDS - Nef-induced CD4 and MHC-I dowregulation plays key role in pediatric HIV progression
Population Genetics - Smallpox in Europe selected for genetic mutation that confers resistance to HIV
Probiotic Activity - The pharmacology of probiotics is not simple; action, side-effects need study
Rankings - Pharmaceutical company scientist named on "Scientific American 50" list
Smallpox Vaccine - Safer smallpox vaccination regimen modeled for HIV-1-infected patients
Tuberculosis Vaccine - Danish BCG vaccine-induced disease found in HIV-infected children
West Nile Virus - Company gets $4.3 from NHLBI to pursue licensure of WNV nucleic acid test
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