Published in AIDS Weekly, December 15th, 2003
P. carinii "causes severe pneumonia in immunocompromised hosts," scientists in the United States explained. "The binding of P. carinii to alveolar epithelial cells and extracellular matrix constituents such as fibronectin and vitronectin is a central feature of infection, which initiates proliferation of the organism."
In a recent study, T.J. Kottom and colleagues at the Mayo Clinic found that "P. carinii binding to lung cells specifically alters the gene expression of the organism, regulating fungal...
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