Published in AIDS Weekly, January 5th, 2004
"Human immunodeficiency virus (HIV) RNase H activity is essential for the synthesis of viral DNA by HIV reverse transcriptase (HIV-RT)," scientists in California explained. "RNA cleavage by RNase H requires the presence of divalent metal ions, but the role of metal ions in the mechanism of RNA cleavage has not been resolved."
In their study, K. Klumpp and colleagues working at Roche Palo Alto LLC "measured HIV RNase H activity associated with HIV-RT protein in the presence of different concentrations of either Mg2+,...
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