Published in AIDS Weekly, February 9th, 2004
Under this IND, Gilead plans to assess the oral bioavailability, pharmacokinetics, safety, and efficacy of GS 9005 in healthy volunteers and HIV- positive patients. GS 9005 is a novel HIV protease inhibitor (PI) discovered at Gilead. Based on data from preclinical and in vitro studies, GS 9005 has the potential to be dosed as a single pill once daily and may have a clinical resistance profile that is distinct from commercially available drugs in the PI...
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