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HIV/AIDS Cancer

Low B-cell counts linked to heightened Kaposi sarcoma risk

Published in AIDS Weekly, February 9th, 2004

Low B-cell counts have been linked to a heightened risk of KS in HIV/AIDS patients.

According to recent research from England, "Infection with HIV-1 is known to impair B-cell function."

"To further elucidate the role of B cells during infection and tumorigenesis," J. Stebbing and coauthors at Chelsea and Westminster Hospital in London "studied their numbers in cases of AIDS-related Kaposi sarcoma (KS) during the HAART era."

"Patients with AIDS-related KS were identified from a database of 4,480 HIV-1 positive individuals and the incidence of KS and rate ratio was stratified according to nadir number of B cells, measured as the...

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