Published in AIDS Weekly, February 9th, 2004
"Cellular interactions between antigen-presenting cells and activated CD4+ T cells are central to the regulation of adaptive immunity," immunologists in the United States explained. "Among the many receptor-ligand pairs involved, the critical importance of CD40-CD40 ligand (CD40L) interactions has been demonstrated in many experimental systems."
"Dysregulation of antigen-presenting cell function is a hallmark of HIV-associated defects in cell-mediated immunity," noted C. Chougnet and colleagues at the Cincinnati Children's Hospital. "Much evidence suggests a...
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