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Immune Reconstitution

Phase I trial of CYT 99 007 initiated

Published in AIDS Weekly, February 9th, 2004

After U.S. Food and Drug Administration (FDA) approval of its investigational new drug (IND) application, Cytheris announced the entry of its first recombinant protein in a phase I clinical study.

CYT 99 007 is a recombinant human Interleukin-7 developed by Cytheris. This cytokine targets the immune reconstitution of immuno-compromised patients, undergoing cancer treatment, affected by AIDS, or recovering from a bone marrow transplant.

This first phase I is performed in Bethesda, Maryland, in cooperation with National Cancer Institute investigators. The clinical trial, including oncology patients, will evaluate the safety, the immune effects, and...

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