HIV/AIDS Therapy
Lipid membranes likely involved in enfuvirtide activity
Published in AIDS Weekly, March 1st, 2004
According to recent research from Portugal, "Partition of the intrinsically fluorescent HIV fusion inhibitor enfuvirtide into lipidic membranes is relatively high (DeltaG=6.6 kcal/mol) and modulated by cholesterol."
"A shallow position in the lipidic matrix makes it readily available for interaction with gp41," reported S. Veiga and coauthors at the University of Lisbon. "No conformational energetic barrier prevents enfuvirtide from being active in both aqueous solution and lipidic membranes."
"Lipidic membranes may play a key role in the...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of AIDS Weekly
Source: AIDS Weekly (2004-03-01)
More Articles from AIDS Weekly
- HIV/AIDS Gene Therapy
Novel gp41-derived peptides inhibit HIV cell entry - Pediatric HIV/AIDS
HAART induces abnormal bone metabolism, reduces BMD in children - HIV/AIDS
Microbead-conjugated anti-gp41 antibodies can isolate HIV-infected cells - HIV/AIDS Pathogenesis
C-type lectin DC-SIGN microdomains enable HIV entry - HIV/AIDS Therapy
T-20 cross-reactive gp41 antibody does not reduce T-20 efficacy - AIDS Therapy
Three-year data highlight Viread efficacy, safety, and side effect profile - More from this issue of AIDS Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
