AIDS Therapy

Three-year data highlight Viread efficacy, safety, and side effect profile

Published in AIDS Weekly, March 1st, 2004

Gilead Sciences, Inc., (GILD) announced preliminary 3-year (144-week) data from a double-blind, phase III clinical trial (Study 903) suggesting that Viread (tenofovir disoproxil fumarate) is associated with similar levels of viral load suppression and a similar renal safety profile when compared to treatment with stavudine (d4T).

At 144 weeks, treatment with stavudine was associated with greater elevations in fasting triglyceride and cholesterol levels and a notably higher incidence of investigator-defined lipodystrophy compared to treatment with Viread. These findings further extend the data from the 48- and 96-week analyses.

The company anticipates...

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Source: AIDS Weekly (2004-03-01)

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