HIV/AIDS Immunity

T-cell Fas expression may predict virological outcome

Published in AIDS Weekly, March 15th, 2004

T-cell Fas expression may predict viral control in patients undergoing HIV treatment.

In a recent study from Seattle, the "role of T-cell immunity in virus control during chronic infection was examined in 79 human immunodeficiency virus type 1 (HIV-1)-infected subjects randomized to receive antiretroviral therapy."

"HIV-1 p24-specific responses were detected in 20% of the subjects at baseline, increasing to 28% of the subjects at weeks 16-24," reported U. Malhotra and coauthors at the Fred Hutchinson Cancer Research Center.

"Induction of virologic suppression was associated with lower plasma HIV-1 RNA levels and a higher...

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Source: AIDS Weekly (2004-03-15)

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