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AIDS Weekly

Susan Hasty, Publisher

Table of Contents . . . March 22nd, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly | Other Publications

Drug Development - PBD hybrids disrupt HIV RNA activity

Drug Development - PRO 542 shows promise as HIV salvage therapy

Drug Development - Benzothiepine and benzazepine derivatives show promise as oral CCR5 blockers

Drug Development - Small molecules with novel antiretroviral mechanisms developed

HIV/AIDS Dementia - Elevated ceramide production may underlie HIV neurotoxicity

HIV/AIDS Dementia - JNK/p38 inhibitors may protect against HIV-induced CNS disease

Biotechnology - DNA chip offers simultaneous detection of HIV, HBV and HCV in blood

Business Update - Distribution agreement dispute resolved for OraQuick Rapid HIV-1 Antibody Test

Drug Development - Novel nevirapine-like agents have improved activity against NNRTI-resistant HIV

Finance - NIH funds development of topical drug to protect from HIV, STDs

Finance - Three Maryland groups share part of federal AIDS grant

HIV/AIDS - Megestrol acetate NCD oral suspension NDA planned for third quarter 2004

HIV/AIDS - Mother of AIDS victim ordered to pay for lying to son's fiance

HIV/AIDS - Novel SIV strain isolated from Schmidt's guenon

HIV/AIDS Animal Models - Macaque SHIV model could aid research on env gene, pediatric infection

HIV/AIDS Cancer - HIV Tat linked to liver tumor development

HIV/AIDS Cancer - PAX2 plays key role in Kaposi sarcoma pathogenesis

HIV/AIDS Complications - VEGF levels rise in the serum of patients with HIV-linked neurological disease

HIV/AIDS Diagnosis - Indian finds AIDS diagnosis was wrong after killing family in despair

HIV/AIDS Drug Resistance - Different resistance mutations seen in blood and lungs of HIV patients

HIV/AIDS Drug Resistance - Peptide insertions in pol are rare cause of ART failure

HIV/AIDS Epidemiology - Frequency of AIDS prevention by restriction genes determined

HIV/AIDS Epidemiology - HIV rates high in both rural and urban Central African Republic

HIV/AIDS Opportunistic Infection - Cryptococcal meningitis prophylaxis not needed after immune recovery

HIV/AIDS Opportunistic Infection - Sulfadiazine pharmacokinetics similar when given two or four times a day

HIV/AIDS Pathogenesis - T-cell subsets harboring HIV in vivo have implications for HIV pathogenesis

HIV/AIDS Prevention - China, U.S. launch joint anti-AIDS program

HIV/AIDS Therapy - Effects of ART on sCD27 expression elucidated

HIV/AIDS Therapy - Lopinavir pharmacokinetics evaluated during Kaletra treatment

HIV/AIDS Therapy - Novel assay enables ddATP monitoring in ddI-treated patients

HIV/AIDS Therapy - Saquinavir exposure enhanced in HIV patients with diarrhea or wasting syndrome

HIV/AIDS Treatment - Dubuque mother and daughter to Africa as AIDS delegates

HIV/AIDS Trends - More than 11% Alabama AIDS cases among over-50s

HIV/AIDS Tuberculosis - PZA pharmacokinetics elucidated in HIV-TB patients

HIV/AIDS Vaccine - HIV vaccine antibodies bind more poorly than natural infection antibodies

HIV/AIDS Vaccine - SIV promoter exchange creates strain that protects against viral challenge

HIV/AIDS Women's Health - Oral lesions in HIV-positive women reduced in HAART therapy

Healthcare Access - Europe, Central Asia countries pledge "universal access" to HIV/AIDS treatment by 2005

Infectious Disease - Experts urge tools to protect women's health

Kaposi Sarcoma - KSHV K1 protein activates Akt cell survival pathway

Neuroscience - JAK2-STAT5 signaling needed for microglia activation by IL-3

Patents - Patent granted for AIDS treatment

Personnel - Development expert Robert Hecht to join AIDS vaccine nonprofit

Sexual Violence - Group says South African government's inaction hurts rape survivors

Spermicide - Condom retailer first to ban products containing nonoxynol-9

Stem-Cell Transplantation - Post-SCT eosinophilic pustular folliculitis described

Substance Abuse - Crystal methamphetamine use increases HIV risk

Virology - RNA molecules play important role as antiviral agents for cell treatment

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