Immunology

Adaptive regulatory T cells suppress killing of persistently infected cells

Published in AIDS Weekly, April 5th, 2004

Scientists report that they have identified a cellular mechanism that prevents the immune system from destroying chronic, incurable viral infections such as herpes, hepatitis and human immunodeficiency virus (HIV).

The research, published in Immunity, explains why critical immune cells fail to act against the viral infection and demonstrates a successful intervention that facilitates elimination of the virus. The results open up exciting new avenues for design of future antiviral therapeutics.

Many human viruses are able to evade the immune system during acute infection and establish long-term persistent infections that are extremely difficult...

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Source: AIDS Weekly (2004-04-05)

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