AIDS Weekly
Susan Hasty, Publisher
Table of Contents . . . April 19th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in AIDS Weekly | Other Publications
Drug Development - Lipophilic substitutions improve benzylpyrazole CCR5 antagonists
HIV/AIDS Protein Research - Chimeric HIV/SIV provides stable trimeric HIV Env for study
Drug Development - Anti-HIV activity of linear peptide gp120 inhibitors characterized
HIV/AIDS Immune Control - IL-15 levels elevated in patients with discordant response to treatment
HIV/AIDS Immune Control - Scavenger function of CCR5Delta32 protein involved in protection from HIV
HIV/AIDS Therapy - MALDI-TOF MS assay provides improved NRTI monitoring
AIDS - NIH grant to be used to develop novel anti-HIV therapeutics
Business Update - Genomics company "sharpens" focus, announces layoffs; CEO to retire
Disease Transmission - Program teaches health workers about preventing mother-to-child HIV infection
Drug Development - Targeting inactive RNA conformation effective drug design strategy
Gene Therapy Vectors - Sheep retrovirus Env efficiently pseudotypes HIV-based lentiviral vectors
HIV Prevention - FDA accepts IND for unique HIV vaccine
HIV/AIDS - At-Home hepatitis C, instant cholesterol, allergen, and HIV test announced
HIV/AIDS - Australian doctors lose appeal against woman who caught HIV from her husband
HIV/AIDS - Cambodian sex workers turn down Bill Gates-funded HIV drug
HIV/AIDS - Company ships 100,000 Rapid HIV test kits to China, first of 1.3 million order
HIV/AIDS - Efforts to get AIDS medications to developing countries may be near breakthrough
HIV/AIDS - FDA approves test to detect HIV-2 antibodies
HIV/AIDS - HIV/AIDS prevention efforts increase in Wyoming
HIV/AIDS - South Carolina gets $19 million for AIDS research and treatment
HIV/AIDS Diagnosis - Doubly indeterminate HIV Western blot results are negative
HIV/AIDS Drug Resistance - Fitness loss caused by HIV resistance mutations may account for low viremia
HIV/AIDS Drug Resistance - Prevalence of HIV resistance mutations in Brazil determined
HIV/AIDS Genomics and Genetics - "Somatic hypermutation" hypothesis for HIV R5-X4 switch proposed
HIV/AIDS Genomics and Genetics - Mutation rates of HIV genomes clarified
HIV/AIDS Opportunistic Infection - Aeration augments Aspergillus fumigatus gliotoxin production in vitro
HIV/AIDS Opportunistic Infection - Antisera-based immunoassay effective for aspergillosis diagnosis
HIV/AIDS Pathogenesis - Ability of HIV LysRS to bind tRNA determines virion packaging efficiency
HIV/AIDS Pathogenesis - Expansion of tumor antigen-specific T cells in transgenic mice reported
HIV/AIDS Prevention - AIDS virus is vulnerable in initial stage of infection
HIV/AIDS Risk - Biology, not behavior, could explain reduced risk of HIV for circumcised men
HIV/AIDS Therapy - Enfuvirtide is new fusion inhibitor for HIV infection treatment
HIV/AIDS Vaccine - Assays with extended incubation phases needed to monitor HIV vaccine trials
HIV/AIDS Vaccine - HIV-1 infection blocked via CCR5 and CXCR4 receptors
HIV/AIDS Vertical Transmission - Girls may have heightened risk of intrauterine HIV infection
HIV/AIDS Vertical Transmission - Mortality from formula use and vertical HIV transmission comparable
HIV/HCV Coinfection - Undetectable HCV viremia and normal liver enzyme levels may not mark cure
Kaposi Sarcoma - Activity of KSHV K8.1 late promoter characterized
Kaposi Sarcoma - KSHV-encoded vIRF-3 activates transcriptional activity of cellular IRF-3/IRF-7
Kaposi Sarcoma - Strong IgG antibody activity linked to high HHV-8 viremia
Medical Errors - Maryland General still looking for 180 patients for retesting
Needlestick Injury - Young doctors face suture needlestick injury risk, survey shows
Patents - Global patents for Fosrenol sold to Shire Pharmaceuticals
Personnel - Emory gains prominent researchers from nearby Birmingham
Proteomics - HB autoantigen is the barrier-to-autointegration factor
Pulmonary Tuberculosis - Multifocal lupus vulgaris preceding pulmonary TB reported
Sepsis - Company receives preclinical report on MDI-P
Sleeping Sickness - IND submitted to FDA for DB289
Transplant Medicine - Method to remove virus from bones, tissues for transplants questioned
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