AIDS/HIV Vaccine
Low-dose mucosal SIV challenge has same kinetics as high-dose challenge
Published in AIDS Weekly, May 3rd, 2004
According to published research from the United States, "Simian immunodeficiency virus (SIV) challenge of rhesus macaques provides a relevant model for the assessment of human immunodeficiency virus (HIV) vaccine strategies. To ensure that all macaques become infected, the vaccinees and controls are exposed to large doses of pathogenic SIV. These nonphysiological high-dose challenges may adversely affect vaccine evaluation by overwhelming potentially efficacious vaccine responses.
"To determine...
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Source: AIDS Weekly (2004-05-03)
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