HIV/AIDS

Indinavir/ritonavir less effective than lopinavir/ritonavir as first-line HAART

Published in AIDS Weekly, May 24th, 2004

Indinavir/ritonavir less effective than lopinavir/ritonavir as first-line HAART in HIV-1-infected patients.

Immunovirological "outcomes and toxicities of HAART regimens, including Lopinavir (LPV)/ritonavir (r) and indinavir (IDV)/r," were compared in antiretroviral naive HIV-1 patients. Fifty-five and 52 patients, respectively, were selected to start LPV/r or IDV/r as first-line HAART, according to research in Italy.

"Immunovirological and metabolic parameters were recorded at baseline and every 3 months as were side effects, AIDS-defining events and deaths. Demographic characteristics and NRTIs included in the regimens were comparable," wrote M....

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Source: AIDS Weekly (2004-05-24)

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