Molecular Virology

Cells provide cues enabling successful viral integration

Published in AIDS Weekly, May 24th, 2004

Cells provide cues that enable successful viral integration.

"Viruses replicate within living cells and use the cellular machinery for the synthesis of their genome and other components. To gain access, they have evolved a variety of elegant mechanisms to deliver their genes and accessory proteins into the host cell," wrote scientists in Switzerland.

"Many animal viruses take advantage of endocytic pathways and rely on the cell to guide them through a complex entry and uncoating program," A.E. Smith and colleagues reported.

"In the dialogue between the cell and the intruder, the cell provides critical cues that allow the virus to...

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Source: AIDS Weekly (2004-05-24)

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