AIDS/HIV Vaccine

Immune efficiency correlates with specific targeting

Published in AIDS Weekly, May 24th, 2004

Immune efficiency correlates with specific targeting.

According to recent research published in the Journal of Virology, "An understanding of the relationship between the breadth and magnitude of T-cell epitope responses and viral loads is important for the design of effective vaccines. For this study, we screened a cohort of 46 subtype C human immunodeficiency virus type 1 (HIV-1)-infected individuals for T-cell responses against a panel of peptides corresponding to the complete subtype C genome. We used a gamma interferon ELISPOT assay to explore the hypothesis that patterns of T-cell responses across the expressed HIV-1 genome correlate with viral...

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Source: AIDS Weekly (2004-05-24)

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