HIV/AIDS Treatment

Deep salvage with amprenavir and lopinavir/ritonavir partially effective

Published in AIDS Weekly, May 31st, 2004

Deep salvage with amprenavir and lopinavir/ritonavir is partially effective.

"The safety, efficacy, and mutual interactions of combination amprenavir with lopinavir/ritonavir as deep salvage treatment were investigated in a prospective 24-week pilot study," scientists in Italy reported.

A. Deluca and colleagues explained, "HIV-infected patients (n = 22) with virologic failure to nucleoside reverse transcriptase inhibitors (NRTIs), non-NRTIs, and at least 2 protease inhibitors received 400/100 mg of lopinavir/ritonavir with 600 mg of amprenavir every 12 hours combined with NRTIs. Patients receiving the same doses of lopinavir/ritonavir (n = 10) or...

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Source: AIDS Weekly (2004-05-31)

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