Retrovirus

Close association between immune response and SIV encephalitis in macaques

Published in AIDS Weekly, May 31st, 2004

There is a close association between immune response and SIV encephalitis in macaques.

"Infection of pig-tailed macaques with the simian immunodeficiency virus (SIV) isolate SIVsmmFGb frequently results in SIV encephalitis (SIVE) in addition to immunodeficiency and acquired immune deficiency syndrome. We used in situ hybridization to quantitate the number of SIV-infected cells in brain parenchyma, choroid plexus, and meninges from 17 macaques that developed acquired immune deficiency syndrome after infection with SIVsmmFGb," wrote scientists at the Yerkes National Primate Research Center.

"SIV-infected cells and histopathological lesions of...

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Source: AIDS Weekly (2004-05-31)

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