Published in AIDS Weekly, June 14th, 2004
"Chronic renal injury can be mediated by angiotensin II (ANG II) and prostanoids through hemodynamic and inflammatory mechanisms and attenuated by individual suppression of these mediators. In rats with 5/6 renal ablation (Nx), we investigated 1) the intrarenal distribution of COX-2, ANG II, and the AT(1) receptor (AT1 R); 2) the renoprotective and antiinflammatory effects of an association between the AT1 R blocker, losartan (Los), and the gastric sparing anti-inflammatory nitroflurbiprofen (NOF)," researchers in Brazil report.
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of AIDS Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.