Angiology
DDR1/DDR2 potential role in obstructive diseases of blood vessels and lungs
Published in AIDS Weekly, July 5th, 2004
According to a study from the United States, "Obstructive diseases of blood vessels and the lung are characterized by degradation and synthesis of new extracellular matrix (ECM) components. Regulated remodeling of the ECM in diseases such as atherosclerosis and lymphangioleiomyomatosis (LAM), both characterized by excessive accumulation of smooth muscle cells (SMCs), is thought to be controlled in part by cell surface receptors for specific ECM components."
"Discoidin domain receptors (DDR) 1 and 2 represent a family of tyrosine kinase...
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Source: AIDS Weekly (2004-07-05)
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