HIV/AIDS-Associated Infection
IFN-gamma activates monocytes for enhanced phagocytosis of M. avium in HIV
Published in AIDS Weekly, July 26th, 2004
"Defective immunological function of cells of the macrophage lineage contributes to the pathogenesis of HIV-1 infection. Because monocyte/macrophage function is enhanced by cytokines such as interferon-gamma (IFN-gamma), the use of this immunomodulator is of potential clinical interest as adjunctive immunotherapy in immunosuppressed individuals," wrote scientists in Australia.
"In this study," K. Kedzierska and colleagues reported, "we show that adjunctive IFN-gamma treatment in an HIV-infected individual with Mycobacterium avium...
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Source: AIDS Weekly (2004-07-26)
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