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AIDS Weekly

Susan Hasty, Publisher

Table of Contents . . . August 9th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly | Other Publications

HIV/AIDS Blood Safety - Nucleic acid testing for HIV-1 and HIV-2 increases safety of donated blood

HIV/AIDS Prognostics - T cell activation/maturation help predict treatment response in HIV infection

HIV/AIDS Research - HIV-1 RNA level in cervical secretions influenced by menstrual cycle

HIV/AIDS Research - Minor baseline HIV protease mutation predict 90M mutation at virological failure

AIDS Therapy - NAFTA officials back generic AIDS drugs for poor nations

AIDS/HIV - AIDS-related episodes on TV program increase calls to CDC AIDS hotline

AIDS/HIV Therapy - Protective T-cell epitope in p15gag of leukemia virus identified

Abortion - Africa: Efforts to prevent unsafe abortions fall short, especially for HIV+

Allergy & Immunology - Novel mechanism used by infectious agents subverts first line of host defense

Antimicrobial Resistance - MRSA and vancomycin-resistant enterococci associated with adverse outcomes

Antiretroviral Therapy - I50L is signature mutation for ATV resistance in treatment-naive HIV-1-infection

Antiretroviral Therapy - Stability and activity of ADAM NNRTIs improved

Business Update - Supply company signs agreement with Bayer Diagnostics

Cervical Cancer - Common therapy for HIV associated with cervical abnormality regression

Collaborations - siRNA deal expanded, candidates chosen for development against HIV

Contraception - Use of birth control by HIV positive women in France evaluated

Diagnostics -  T. vaginalis infection in men detected by sampling multiple genitourinary sites

Diagnostics - Molecular diagnostics tests provided to Quest Diagnostics

Drug Development - New database will contain published, unpublished HIV protein info

Evolutionary Biology - HIV reveals evolution of a primate defense against intragenomic infiltrators

Finance - Viral disease-focused company provides preliminary second quarter results

HIV Prevention - New HIV entry inhibitor drug candidate to advance to phase II

HIV Therapy - Tipranavir safety, pharmacokinetics data reported at AIDS conference

HIV/AIDS - Africa: Vaginal gel promising for HIV prevention

HIV/AIDS - CEO asserts patent protection is crucial for next generation HIV/AIDS medicines

HIV/AIDS - Company reports negative results for phase III HIV/AIDS study

HIV/AIDS - Data offers best HIV RNA response in given highly active antiretroviral therapy

HIV/AIDS - Female peer educators in Djibouti emphasize change in sexual behavior

HIV/AIDS - Four new AIDS medicines added to the WHO prequalification list

HIV/AIDS - Fuzeon-based therapy provides significant long-term benefit

HIV/AIDS - Interim analysis of a Phase IIb study of tipranavir in HIV-positive patients

HIV/AIDS - Microbicide research at USAID gets funding boost in House bill

HIV/AIDS - Mothers, babies in South Africa will continue nevirapine monotherapy for now

HIV/AIDS - Pharma company presents clinical data HIV drugs, including PA-457

HIV/AIDS - REYATAZ received FDA approval to include new data and dosing in package insert

HIV/AIDS - Reverset clinical trial results presented at AIDS conference

HIV/AIDS - Studies Viread and Emtriva published in JAMA

HIV/AIDS - UN official says only empowering women can slow AIDS epidemic in Africa

HIV/AIDS - UN: Action against AIDS must address epidemic's increasing effect on women

HIV/AIDS - West African community joins network of community-based treatment support programs

HIV/AIDS & Heart Disease - CABG for unstable angina does not effect CD4 cells and HIV viral load

HIV/AIDS Diagnostics - Clinical trials begin for HIV lateral flow rapid tests

HIV/AIDS Diagnostics - HIV-1 subtype G detected using Cobas ampliscreen test

HIV/AIDS Epidemiology - CDC reports stability of HIV rates among older Americans

HIV/AIDS Funding - UNAIDS welcomes U.K.'s new 1.5 billion pound AIDS strategy

HIV/AIDS Managed Care - Solid organ transplantation in HIV-infected patients feasible in era of HAART

HIV/AIDS Prevention - Foundation launches major initiative to prevent spread of HIV

HIV/AIDS Prevention - HIV trends among men who have sex with men reported at AIDS conference

HIV/AIDS Prevention - Lay health advisor-based AIDS programs successfully employ safe sex practices

HIV/AIDS Prevention - Progress seen in adolescent sexual health

HIV/AIDS Prevention - Treatment availability in Botswana sparks demand for HIV testing services

HIV/AIDS Prevention - U.N.-supported group launches HIV/AIDS media education efforts

HIV/AIDS Prevention - Unique radio drama compels people in Botswana to seek AIDS information

HIV/AIDS Prevention - Yale receives $2.1 million grant for HIV work in India

HIV/AIDS Research - Activated macrophage/microglial cells have neuroprotective role in HIV infection

HIV/AIDS Research - Activated naive B cells in HIV-1 infection down-regulate CXCR5 on their surface

HIV/AIDS Research - Anti-HIV activity found in peptides derived from SDF-1 C-terminal sequence

HIV/AIDS Research - Bidirectional SF2/ASF-/SRp40-dependent ESE regulates HIV-1 rev/env/vpu/nef mRNAs

HIV/AIDS Research - C-terminus alterations of HIV-1 vpr do not correlate to disease intensity

HIV/AIDS Research - Configurations of metallocyclams and relevance to anti-HIV activity elucidated

HIV/AIDS Research - HIV-1 genomes reside within actively transcribed host genes in resting CD4 cells

HIV/AIDS Research - ICAM-3 increases HIV-1 transcription and viral production

HIV/AIDS Research - Nef enhances infectivity of HIV-1 particles produced in primary T cells

HIV/AIDS Research - Proteoglycans contribute to HIV-1 brain invasion

HIV/AIDS Research - SIN HIV-1-based vectors identify synthetic endothelial cell-specific promoters

HIV/AIDS Testing - AtHomeDiagnostics.com offers only FDA-approved HIV test for sale to consumers

HIV/AIDS Testing - New HIV/AIDS tests more accurate, reproducible, cheaper, study shows

HIV/AIDS Therapies - Pharmaceutical firm shares results from programs to fight HIV/AIDS

HIV/AIDS Therapy - South African pharma company granted patent license for HIV/AIDS drug efavirenz

HIV/AIDS Therapy - Study results of protease inhibitor for AIDS presented at conference

HIV/AIDS Therapy - University medical researchers discuss findings at International AIDS Conference

HIV/AIDS Transmission - GMHC addresses meth use and syphilis as they relate to HIV transmission

HIV/AIDS Treatment - Companies to develop co-package of Combivir and Viramune for developing world

HIV/AIDS Vaccine - Biopharma company reports encouraging preliminary HIV/AIDS vaccine results

HIV/AIDS Vaccine - First patients enrolled in HIV vaccine trial

HIV/AIDS Vaccine - Preliminary EP HIV-1090 trial data presented at international AIDS conference

HIV/AIDS Vaccine - Tomatoes may offer edible AIDS vaccine

Hepatitis - Assay proven to ID previously undedectable hepatitis B blood donations

Herpesvirus - Herpesvirus protease inhibited by dimer disruption

Herpesvirus - KSHV-encoded latency-associated NA inhibits lytic replication by targeting Rta

Herpesvirus - Kaposi sarcoma-associated herpesvirus GP K8.1 is dispensable for virus entry

Immunology - Drug company reports data on HIV research at international AIDS conference

Immunology - T-cell differentiation distinct in persistent human virus infection

Influenza A Virus - PB1-F2 creates variably sized pores in planar lipid membranes

Legal Issues - CytRx provides update on Massachusetts Ethics Commission preliminary inquiry

Oral Mucositis - Clinical study of MF5232 for oral mucositis drug yields positive results

Pediatric HIV/AIDS - Antiretroviral treatment raises cholesterol in children

Pharmaceutical & Drug Development - Lymphocytes transformed by EBV-related HSV may be useful for antiviral screening

Pharmaceutical & Drug Development - Novel screening assay identifies antiviral compounds

Pharmaceutical & Drug Development - Protease inhibitor nelfinavir inhibits replication of coronavirus

Prion Diseases - Technology reduces infectious prions from blood prior to transfusion

Pulmonary Hypertension - Pulmonary arterial hypertension guidelines caution calcium channel blocker use

Retrovirology - BAF has roles in chromatin, nuclear structure, and retrovirus integration

Retrovirus - Foamy virus reverse transcriptase has greater polymerase activity than HIV-1 RT

Substance Abuse - HIV treatment programs routinely exclude drug users, experts warn

Transplant Medicine - Illinois first state with law allowing HIV organ transplants

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