Antiretroviral Therapy
Clusiaceae species extracts inhibit HIV-1 reverse transcriptase
Published in AIDS Weekly, August 16th, 2004
"The organic plant extracts of 21 species of Clusiaceae from Mexico were screened for anti HIV-1 reverse transcriptase activity in a nonradioactive immuno colorimetric assay," investigators in Mexico report.
"The extracts of 5 species (23.8%) exhibited significant inhibition ({{>=}}70%) of HIV-1 RT activity; of these," wrote M. Huerta-Reyes and colleagues, "only 4 extracts showed reduced toxicity to human lymphocytic MT2 cells and were further tested as inhibitors of HIV-1 IIIb/LAV replication in a cellular system."
"The best extracts were...
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Source: AIDS Weekly (2004-08-16)
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