HIV/AIDS Pathogenesis
HIV-1 evolution/immunological responses similar at 10 years despite therapies
Published in AIDS Weekly, September 13th, 2004
"Two sexual partners infected with related HIV-1 viruses and enrolled in different therapeutic strategies including structured treatment interruptions (STI) provided us an opportunity to compare long term (10 years) viral genetic evolution for closely related isolates in different hosts," wrote researchers in Spain.
"HLA loci were molecularly typed and different genetic markers were studied. The viral genetic evolution was studied by sequencing pol and env genes. The HIV-specific CD4+ and CD8+ T cell responses were assessed by the...
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Source: AIDS Weekly (2004-09-13)
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